Thymosin alpha-1

Thymosin Alpha-1

• Chemical Identity
  • Alternate Names: Zadaxin™, Thymalfasin, Ta1
  • Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
  • Length: 28 amino acids, derived from the precursor peptide prothymosin α
  • Purity: ≥98–99% depending on supplier
• Appearance & Format
  • Lyophilized white/off-white powder
  • Available in sterile vials, typically in 0.5 mg, 1 mg, or 5 mg sizes
• Biological Role & Mechanism
  • Functions as a biological response modifier, restoring and modulating immune function
  • Enhances T-cell maturation, differentiation, and function
  • Regulates cytokines such as Interleukin-2 and Interleukin-6, supporting immune balance
  • Shown to improve cell-mediated immunity in both animal and human models
• Applications
  • Clinical Use: FDA-approved under the trade name Zadaxin™, used in cancer therapy and viral illnesses
  • Research Use:
• • Immunodeficiency and immune reconstitution studies
  • Anti-aging and “inflammaging” research
  • Cancer immunotherapy combinations
  • Vaccine adjuvant response protocols
  • Sepsis and viral infection models
• Storage & Handling

• Store at -20°C in a cool, dry environment
• Reconstitute with bacteriostatic water for laboratory use
• For research use only unless supplied as FDA-approved formulations

Thymosin alpha-1 stands out as a versatile immunomodulator bridging clinical medicine and advanced research. Its dual role in enhancing immune resilience and supporting therapeutic protocols makes it a valuable peptide for both laboratory studies and medical applications.