Melanotan 1
Overview:
Melanotan 1, also known by its research name Afamelanotide, is a synthetic analog of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH). Unlike cosmetic tanning products, it works by activating melanocortin receptors in the body to encourage natural melanin production.
Key Features:
- Mechanism of Action: Selectively targets MC1 receptors to stimulate melanin synthesis.
- Research Purpose: Initially engineered to explore skin pigmentation regulation and potential protection against UV-related damage.
- Form: Typically supplied as a peptide for research use, often in lyophilized powder form.
- Distinction from Melanotan 2: Melanotan 1 is more specific to pigmentation pathways, while Melanotan 2 has broader effects including appetite and sexual function.
Important Considerations
- Regulatory Status: Melanotan 1 is not FDA- or EMA-approved for general medical or cosmetic use. It remains classified as a research chemical.
- Safety: Reported side effects include nausea, increased pigmentation in unintended areas, and skin darkening.
- Usage Context: Primarily studied in controlled research environments; not recommended for unsupervised or recreational use.


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